Evaluation of Next-Generation Sequencing Platforms for Population Targeted Sequencing Studies

Evaluation of Next-Generation Sequencing Platforms for Population Targeted Sequencing Studies
Samuel Levy, PhD
Translational Genomics, Scripps Translational Science Institute
X-GEN Congress, March 2010

At the March X-GEN Congress, Samuel Levy presented a comparison between Sanger Whole Human Genome and Targeted Genomic Enrichment in NGS. Among his conclusions were that NimbleGen exome capture, coupled with 454 sequencing, provides high coverage of the exome, with increased precision of variants detected (including variants not previously detected by WSG-Sanger sequencing). 

Here are the slides that accompanied his presentation:

 Levy presentation slides, X-GEN 2010